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The prevalence of allergic diseases worldwide is rising dramatically in both developed and developing countries. A steady increase in the prevalence of allergic diseases globally has occurred with about 30-40% of the world population now being affected by one or more allergic conditions.

According to World Health Organization (WHO) statistics, hundreds of millions of subjects in the world suffer from rhinitis and it is estimated that more than 300 million have asthma, markedly affecting the quality of life of these individuals and their families, and negatively impacting the socio-economic welfare of society. It is forecast that allergic problems will increase further as air pollution and the ambient temperature increase. These environmental changes will affect pollen counts, the presence or absence of stinging insects, and the presence or absence of molds associated with allergic diseases.

These diseases include asthma; rhinitis; anaphylaxis; drug, food, and insect allergy; eczema; and urticaria (hives) and angioedema. This increase is especially problematic in children, who are bearing the greatest burden of the rising trend which has occurred over the last two decades.